Spectroscopic and Colorimetric Determination of Meloxicam, Lornoxicam, Tenoxicam in Drugs Spectroscopic and Colorimetric Determination of Meloxicam, Lornoxicam, Tenoxicam in Drugs
Main Article Content
Abstract
New approach to spectrophotometric and colorimetric determination of meloxicam, lornoxicam, tenoxicam in drugs using 7-chloro-4-nitrobenz-2-oxa-1,3-diazole (NBD chloride) is developed. The techniques are based on alkaline hydrolyses of oxicams with NBD chloride and the subsequent spectrophotometric and colorimetric determination of the colored products of reaction. The linearity range of calibration dependence is 1-10 mg/ml for lornoxicam and tenoxicam, 0.5-5 mg/ml for meloxicam. The advantages of developed methods are rapidity and cost-efficiency. This approach can be used for screening control of drug quality.
Downloads
Article Details
This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.