Synthesis, Characterization and Antifungal activity of Certain(E)-1-(1-(substitutedphenyl) ethylidene) - 2 -(6-methylbenzo[d]thiazol-2-yl) hydrazine analogues
In the present study, five new derivatives (R1 to R5) of benzothiazoles were synthesized and were evaluated against four fungal strains: Candida albicans (MTCC 183), Aspergillus niger (MTCC 228), Candida tropicalis (MTCC 6192), and Fusarium oxysporium (MTCC 3656). p-Toluidine on treatment with ammonium thiocynate formed 2-benzothiazolamines, which on reacted with hydrazine hydrate formed a hydrazino derivative. Compounds (R1 to R5) were synthesized by reacting hydrazine derivative with different substituted acetophenones. All the synthesized compounds were identified by IR, 1H-NMR and antifungal activity was performed on the synthesized compounds. The results obtained justify the importance of benzothiazoles in the field of therapeutics
How to Cite
This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.