A Review on Biomolecular Mechanisms of Parkinson’s Disease

Authors

  • P. Sree Mahalakshmi

DOI:

https://doi.org/10.22377/ijpba.v12i1.1917

Abstract

Degeneration of catecholaminergic (dopamine) neurons in the Substantia Nigra pars compacta of the basal ganglia results in Parkinson’s disease (PD). The drug of choice is L-dopa, anticholinergics, amantadine, monoamine oxidase-B inhibitors, dopamine agonists, and catechol O-methyl transferase inhibitors are used. Therapeutic strategies are currently managing the symptoms of PD, but not curing the disease. This review draws insights on the molecular mechanisms driving the loss of brain cells in PD.

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Published

2021-03-15

How to Cite

Mahalakshmi, P. S. . (2021). A Review on Biomolecular Mechanisms of Parkinson’s Disease. International Journal of Pharmaceutical & Biological Archive, 12(1). https://doi.org/10.22377/ijpba.v12i1.1917

Issue

Vol. 12 No. 1 (2021): International Journal of Pharmaceutical and Biological Archive

Section

Review Articles

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.