Evaluation of CNS Depressant Activities of Ethanolic Extract of Ficus bengalensis (Moraceae) Leaves

Authors

  • Md Ashikur Rahman 1Pharmacy Discipline, Khulna University, Khulna-9208, Bangladesh

Abstract

ABSTRACT Phytochemical analysis of the dried leaves of Ficus bengalensis (Moraceae) indicated the presence of flavonoids, alkaloids, triterpenoids, tannins, saponins and steroids. The pharmacological interest of these compounds, coupled with the use of this plant in traditional medicine prompted the authors to check for its possible CNS depressant activities in animal models. METHODS: In CNS depressant test; hole cross, open field, beam walking and thiopental sodium-induced sedative test was studied. RESULTS: In CNS-depressant tests; hole cross, open field, beam walking and thiopental sodium-induced sedative test in mice it significantly (p<0.005, p<0.001) decreased the locomotor activity in mice. CONCLUSION: The obtained results provide a support for the use of this plant in traditional medicine and its further investigation.

Downloads

Download data is not yet available.

Downloads

How to Cite

Ashikur Rahman, M. (2011). Evaluation of CNS Depressant Activities of Ethanolic Extract of Ficus bengalensis (Moraceae) Leaves. International Journal of Pharmaceutical & Biological Archive, 2(3). Retrieved from http://ijpba.info/index.php/ijpba/article/view/278

Issue

Vol. 2 No. 3 (2011): International Journal of Pharmaceutical and Biological Archieve

Section

Research Articles

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.