Formulation and Evaluation of Atenolol Floating Tablets Using Different Polymers: Guargum, Sodium Alginate, Hpmc100cps and Carbopol940

Authors

  • Goyal Eswer 1Department of Pharmaceutics, Nova College of pharmacy, Vegavaram.

Abstract

ABSTRACT: The objective of the present study was to prepare Floating tablets of Atenolol with best polymer. These were developed to prolong the gastric residence time and increase the drug bioavailability .The Tablets were prepared by direct compression technique, using polymers such as Guar gum, Sodium alginate, HPMC-100CPS, Carbopol940, and other standard excipients. Tablets were evaluated for a physical characteristic was evaluated. Hardness, floating capacity, thickness, weight variation and dissolution. Among four polymers studied, Sodium alginate had shown more drug release. Among eight formulations, one (F6) was found to be best of all the trials showing that the drug release matches the brand product.

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How to Cite

Eswer, G. (2011). Formulation and Evaluation of Atenolol Floating Tablets Using Different Polymers: Guargum, Sodium Alginate, Hpmc100cps and Carbopol940. International Journal of Pharmaceutical & Biological Archive, 2(4). Retrieved from http://ijpba.info/index.php/ijpba/article/view/348

Issue

Vol. 2 No. 4 (2011): IJPBA

Section

Research Articles

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.