Formulation and Evaluation of Immediate Release Tablets of Linezolid

Authors

  • K Sai Madhav Reddy Dept of Pharmaceutics, Nova college of pharmacy, Vegavaram, Andhra Pradesh, India.

Abstract

ABSTRACT In this study Immediate Release Tablets of Linezolid were formulated by wet granulation method. Nine formulations (f2-f10) of immediate release oral tablets were prepared by using different disintegrants to get desired release profile as that of reference marketed product (f1). Evalution Parameters Like weight variation, hardness of the tablet,friability,thickness,disintegration test,drug content uniformity and in vitro release studies were performed. Formulation of linezolid having 8.0mg of HPC i.e., Formulation F-10 can be taken as an ideal or optimized formulation.

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How to Cite

Sai Madhav Reddy, K. (2011). Formulation and Evaluation of Immediate Release Tablets of Linezolid. International Journal of Pharmaceutical & Biological Archive, 2(4). Retrieved from http://ijpba.info/index.php/ijpba/article/view/364

Issue

Vol. 2 No. 4 (2011): IJPBA

Section

Research Articles

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.