Protective Effect of Luffa cylindrica L. Fruit in Paracetamol Induced Hepatotoxicity in Rats

Authors

  • N. Balakrishnan Department of Pharmacognosy, Technocrats Institute of Technology-Pharmacy,Bhopal (M.P.) - 462021, India.

Abstract

ABSTRACT In present study to evaluate the hepatoprotective activity of the ethanol and aqueous extracts (100 and 200 mg/kg) of fruit of Luffa cylindrica were studied on paracetamol (2 gm/kg) treated albino rats. The hepatoprotective effect was evaluated on the basis of various biochemical parameters which includes aspartate aminotransferase (AST) and alanine aminotransferase (ALT),serum alkaline phosphatise(ALP), total bilirubin (TB), total cholesterol (TC) and total protein (TP). Treatment with ethanol and aqueous extracts (100 and 200 mg/kg) of fruit of Luffa cylindrical shown significant hepatoprotective effect and also supported by histopathological study.

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How to Cite

Balakrishnan, N. (2012). Protective Effect of Luffa cylindrica L. Fruit in Paracetamol Induced Hepatotoxicity in Rats. International Journal of Pharmaceutical & Biological Archive, 2(6). Retrieved from http://ijpba.info/index.php/ijpba/article/view/500

Issue

Vol. 2 No. 6 (2011): International Journal of Pharmaceutical and Biological Archives

Section

Research Articles

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.