Simultaneous Equation Method for Simultaneous Estimation of Paracetamol and Ibuprofen in Combined Dosage Form.

Authors

  • Tapan Giri

Abstract

A simple reproducible simultaneous equation method, requiring no prior separation, has been developed for the estimation of ibuprofen and paracetamol in combined dosage form. Ibuprofen has absorbance maxima at 220 nm and paracetamol at 248.40 nm using ethanol as solvent. The method obeys Beer’s Law in concentration ranges employed for the estimation. The results of the analysis were validated statistically and recovery studies were carried out as per ICH guidelines. Also the developed method was successfully employed for dissolution studies in tablet dosage form.

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How to Cite

Giri, T. (2010). Simultaneous Equation Method for Simultaneous Estimation of Paracetamol and Ibuprofen in Combined Dosage Form. International Journal of Pharmaceutical & Biological Archive, 1(2). Retrieved from http://ijpba.info/index.php/ijpba/article/view/56

Issue

Vol. 1 No. 2 (2010): IJPBA

Section

Short Communication

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.