Immunohistochemical Study of Placentas of Pregnant Women with Hypothyroidism Compared to Healthy Individuals in Zahedan City
Main Article Content
Abstract
Background: Thyroid hormones are crucial for fetal health and placental development. Aim: To investigate
immunohistochemical changes in placentas of pregnant women with hypothyroidism compared to healthy
individuals. Materials and Methods: A total of 200 placentas (100 hypothyroid and 100 healthy)
were analyzed for histopathological parameters including syncytial nodes, hyalinization, calcification,
and cytotrophoblastic proliferation. Results: All studied parameters were significantly higher in the
hypothyroid group compared to controls. Conclusion: Hypothyroidism during pregnancy significantly
affects placental morphology, emphasizing the need for early diagnosis and treatment.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.