Antifertility Activity of Aqueous Leaf Extract of Andrographis paniculata in Male Albino Rats

Authors

  • B Senthil kumar Department of Zoology, Thiruvalluvar University,Serkadu, Vellore-632106. (Tamilnadu)India.

Abstract

ABSTRACT The present study was to evaluate the effect of antifertility in aqueous leaf extract of Andrographis paniculata has been studied in Albino Rat. The study was divided into three groups of six animals for each. The first group (I) received distilled water serve as control. The second and third groups (II and III) of animals were administered the aqueous leaf extract daily on 100mg/kg body wt., and 200mg/kg body wt., respectively for a period of 45days significant decreases in the weights of testis, epididymes and seminal vesicle were observed. A dose related reduction in the testicular sperm count, epididymal sperm count and motility and abnormal sperm count were observed. The results suggest that the aqueous extract of the leaves of Andrographis paniculata has spermicidal activity.

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How to Cite

Senthil kumar, B. (2011). Antifertility Activity of Aqueous Leaf Extract of Andrographis paniculata in Male Albino Rats. International Journal of Pharmaceutical & Biological Archive, 2(4). Retrieved from http://ijpba.info/index.php/ijpba/article/view/355

Issue

Vol. 2 No. 4 (2011): IJPBA

Section

Research Articles

License

This is an Open Access article distributed under the terms of the Attribution-Noncommercial 4.0 International License [CC BY-NC 4.0], which requires that reusers give credit to the creator. It allows reusers to distribute, remix, adapt, and build upon the material in any medium or format, for noncommercial purposes only.